Best CPAP Machines of 2022: Comparing Our Best-Selling CPAP Machines

There are a lot of factors that go into selecting a CPAP machine for your therapy needs. Our experts have reviewed some of the top-rated CPAP machines and their features and benefits to help make it easier to choose a CPAP machine that’s right for you.

Best CPAP Machines of 2022

Best CPAP Machines Comparison Chart 2022

2022 CPAP MachineResMed AirSense 10 AutoSet Card-to-CloudResMed AirSense 11 AutoSet3B Medical Luna G3 ResMed AirMini Travel
Size4.57″ x 10.04″ x 5.91″10.21” x 3.72” x 5.45”10.4” × 5.7” × 4.4”5.4″ x 3.3″ x 2.1″
Weight2.75 lbs2.5 lbs3.75 lbs.66 lbs
Noise Level27 dBA27 dBA26 dBA30 dBA
Pressure Range4 to 20 cm H2O4 to 20cm H204 to 20 cm H2O4 to 20 cm H2O
Exhale Pressure ReliefYesYesYesYes
Leak CompensationNoNoNoNo
Average Customer Rating4 ½ starsNANA4 ½ stars
 Buy NowBuy NowBuy NowBuy Now

ResMed AirSense 10 AutoSet Card-to-Cloud CPAP Machine


  • Adjustable humidification
  • User friendly interface
  • Connected Care support


  • Bulkier unit
  • No cellular connectivity

Editor Review

The ResMed AirSense 10 Card-to-Cloud CPAP Machine includes all the same features and parts as the original AirSense 10, minus the cellular connectivity. Instead, this machine includes an SD card to record sleep data that doctors can then upload for review.

Why Should I Buy the ResMed AirSense 10 AutoSet Card-to-Cloud CPAP Machine?

This device is user-friendly and easy for all CPAP patients to use. It includes comfort features like AutoRamp, integrated humidification, and much more. It is also great for users who already have some components of the original AirSense 10, as the parts like the humidifer chamber, tubing, and more are interchangable.

ResMed AirSense 10 AutoSet Card-to-Cloud CPAP Machine

• Features a card-to-cloud service that sends data to the cloud for a patient’s doctor to review

Shop Now

ResMed AirSense 11 AutoSet CPAP Machine with Heated Humidifier


  • Smart heated humidification
  • AutoRamp
  • Expiratory Exhalation Relief


  • No swivel connection for tubing
  • Can only view one night’s worth of sleep data

Editor Review

The enhanced digital health technology makes it simpler to begin therapy for the first time, adjust to your pressure setting, and stay CPAP compliant long term. ResMed took the best features of the AirSense 11’s predecessor, the AirSense 10, and added even more useful features. It is even more sleek and compact than the AirSense 10, designed to fit comfortably into every CPAP user’s lifestyle.

Why Should I Buy ResMed AirSense 11 AutoSet CPAP Machine?

The AirSense 11 includes both the AutoSet and AutoSet for Her algorithms, which are among the most clinically published in the field of sleep-disordered breathing. It works to automatically adjust to each patient’s therapy pressure as their needs change – hourly and nightly– to deliver the patient’s ideal lowest therapy pressure.

ResMed AirSense 11 AutoSet CPAP Machine

• A premium auto-adjusting pressure device that combines enhanced digital health technology with effective therapy modes

Shop Now

3B Medical Luna G3 CPAP Machine


  • Quiet
  • Easy to operate
  • Reliable performance


  • Larger than other models which can make travel with the unit difficult

Editor Review

The Luna G3 is very reliable, and also very quiet. It provides a persistent performance and is a dependable CPAP machine without a lot of bells and whistles, which makes this a good choice for some CPAP users. It includes features like integrated tubing, AutoRamp, and a modern design to help users experience very comfortable therapy.

Why Should I Buy 3B Medical Luna G3 CPAP Machine?

If you are looking for a long-term, high-performing CPAP machine, the 3B Medical Luna G3 delivers. With a user-friendly interface and little maintenance, it is the ideal machine for those who want a reliable, quiet, and consistent CPAP performance.

3B Medical Luna G3 CPAP Machine

• Includes an integrated humidifier, several comfort features and settings, and a lightweight design for comfortable CPAP therapy

Shop Now

ResMed AirMini Travel CPAP Machine


  • Lightweight and ready for travel
  • Lots of features for a travel CPAP machine
  • Waterless humidification


  • Have to operate from smartphone
  • No battery included

Editor Review

For those who travel, the AirMini offers many of the essential features of a home CPAP machine while on the go. The lightweight design makes it easy to pack and the waterless humidifier adds to the ease of CPAP use while away from home. This unit can also double as both a home and travel CPAP. It includes many smart features like AutoStart and AutoStop, AutoRamp, and more.

Why Should I Buy ResMed AirMini Travel CPAP Machine?

Frequent travelers who want to stay CPAP compliant can rely on the AirMini to maintain consistent and comfortable CPAP therapy on the go. The design is FAA approved and provides traveling CPAP patients with a small footprint version of their home model.

ResMed AirMini Travel CPAP

• Provides all the comfort and convenience provided by your home auto CPAP in a small, travel-ready package

Shop Now

What Are the CPAP Machine Accessories Required for Successful CPAP Therapy?

Staying CPAP compliant doesn’t end with your CPAP machine. The best accessories work with your machine to help maintain your health and comfort. 

CPAP Masks

Your CPAP mask is all about personal preference. Some people prefer the coverage of a full face CPAP mask. Others may prefer the lighter nasal mask or the minimal contact of a nasal pillow mask.


Your CPAP hose connects you to your CPAP machine.  Longer and more flexible hoses give you more freedom of movement. Heated hoses can warm the airflow for more comfort.


Humidifiers moisten the airflow to prevent dry nose and throat the morning after CPAP therapy. It results in a more comfortable experience so users can sleep better at night. Most newer models of CPAP machines include an integrated humidifier to provide the most effective treatment.

External Battery

Portable CPAP machines help you stay compliant while away from home. External batteries give your machine power when outlets are not available. You can use your machine on camping trips and other places without power sources with peace of mind.


Filters help keep your CPAP air clean and maintain the performance of your machine. Change your CPAP machine filters as recommended by the manufacturer.

CPAP Machine Cleaner

Keeping your CPAP equipment clean helps prevent infections from germs and bacteria. You can handwash your equipment with soap and water, but a CPAP machine cleaner is faster and easier.

CPAP Pillows

Head position can play an important role in CPAP therapy. CPAP pillows can help you sleep comfortably while providing proper head and neck support.

How to Buy a CPAP Machine

You can shop online for CPAP machines at The CPAP Shop. We offer the latest machines and many more items so CPAP users can have the best therapy for their health and wellbeing. Here are a few things to look for when searching for a CPAP machine.


Find a CPAP machine that fits your budget. The CPAP Shop offers many CPAP machines on sale that provide lasting performance.


To protect your purchase, look for a warranty on your CPAP machine. Most manufacturers offer a limited warranty. The CPAP Shop also offers a 30-day guarantee on your CPAP machine.

Types of Sleep Apnea

Know the different types of sleep apnea to best understand your diagnosis and treatment.

  • Obstructive sleep apnea: caused when your airway closes while you sleep
  • Central sleep apnea: caused when the brain briefly stops sending signals to the muscles that control breathing
  • Mixed sleep apnea: This is a combination of obstructive and central sleep apnea

Doctor’s Prescription

You will need a doctor’s prescription to purchase your CPAP machine. You can submit your prescription to The CPAP Shop and start shopping for your machine.

Compatible CPAP Mask

When you purchase your CPAP machine, also look for a CPAP mask that works for you. Compare masks to find one that is comfortable and compatible with your CPAP machine.

Size of the CPAP Machine

More compact CPAP machines take up less space on your nightstand and can be easily packed for travel. Look for machines that deliver all the latest features in a smaller package.

Pressure Range

Check your doctor’s prescription and make sure your CPAP machine works within the pressure range prescribed. Pressure ranges may change over the course of your treatment, so it’s important to find a machine that offers a broad range.


If you experience a sore throat or dry nose during CPAP therapy, you may need a humidifier. Many CPAP machines come with built-in humidifiers. If your preferred CPAP machine does not have a humidifier, you can purchase an external humidifier.

Ramp Time

Ramp time eases you into your prescribed air pressure. Look for a machine with ramp time to help you gradually get accommodated to higher pressure settings.

Hose Length

For more flexibility choose a longer lose so you can move freely during CPAP therapy. Longer hoses are also helpful for active sleepers.

Noise Level

Some CPAP machines can be noisy. Review decibel levels so you can find a machine that operates quietly. A quieter machine improves sleep for both you and your bed partner.

Operating Altitude

If you travel frequently by air, you may have to use your CPAP machine in flight. Look for CPAP machines that are FAA approved and provide operating altitudes that fit your travel plans.

Power Source

Most CPAP machines include DC power for home use. You can also find machines that can be charged in your car or on your boat or use external batteries when no power source is available. Select a power source option that fits your lifestyle.


Alerts help you stay informed about changes in your CPAP machine performance. These alerts can tell you when there is a mask leak, when your batteries are low, or when there is a respiratory event.


Easy-to-use controls are especially helpful for those who are not tech-savvy. Most CPAP machines feature user-friendly LED control panels to make operating and setting the machine easier than ever.

Sleep Data

You can track the success of your CPAP therapy over time by examining your sleep data. Choose a CPAP machine that collects this information. By reviewing your sleep data, you can see where you are experiencing sleep apnea spikes and how adjusting pressure settings helps minimize those events.

How Often Should You Replace your CPAP Machine?

It is usually time to replace your CPAP machine after five years of use. To maintain the highest level of CPAP compliance, you want your CPAP machine at peak performance, and replacing it after 5 years ensures continued CPAP therapy success.

What CPAP Machine Should I Buy?

You have your pick of CPAP machines, depending on your needs and lifestyle. Travel CPAP machines are great for travelers who want to stay CPAP compliant. Home CPAP machines are perfect for home use, BiPAP machines are especially helpful for patients who have comfort difficulties with standard CPAP machines.

How to Set up my CPAP Machine

Most CPAP machines are easy to set up.

  1. Attach the hose
  2. Attach and adjust the mask
  3. Plug in the machine to a power source
  4. Turn on the humidifier if needed
  5. Adjust ramp settings if needed

What’s New in CPAP Machines? 

High-tech advances in CPAP machines include sleep data collection so you can track your CPAP therapy. Bluetooth connectivity can also get you troubleshooting, and adjustment help for your machine from an expert team. Not all CPAP machines offer these perks, so if they are important to you, look for these features before you purchase.

Do CPAP Machines Come with Warranties?

CPAP machines typically come with 2-5 year warranties depending on the manufacturer and the type of CPAP machine you want to buy. Be sure to review the terms of any warranty before you make your purchase.

Where Can I Buy A CPAP Machine?

You can find the reviewed CPAP machines at The CPAP Shop. Our knowledgeable staff can help you select the CPAP machine that best fits your therapy needs. Give us a call at 866-414-9700.

Chris Vasta CPAP Expert & President at The CPAP Shop


Chris Vasta

Over a 10+ year career at PHH Mortgage managing a $100 million portfolio, Chris Vasta learned the ins and outs of the business world. He learned how to establish business relationships, lead a multi-prong team, and implement strategies for long-term growth. In 2007, Vasta used that experience to transition his role into president of The CPAP Shop. Over his tenure, Vasta has been involved in everything from website design to warehouse layout. His hands-on approach with customers has evolved into an in-depth understanding of the challenges of beginning and adhering to sleep therapy. He often provides his insights on product…

0 Comments Leave new

Leave A Comment

Your email address will not be published.