cleaning items on blue background

How to Clean Your CPAP in 2026: The Ultimate Maintenance Guide

Key Takeaways

  • Emptying your water chamber every single morning and allowing it to air dry is the most effective way to prevent the growth of pink slime (Serratia marcescens) and mold.

  • For supplemental sanitizing, stick to UV-C LED technology; it is faster, chemical-free, and—unlike Ozone—it will not damage the internal silicone or foam of your 2026 machine.

  • Change your fine-particle filters every 30 days (or sooner if you have pets); a clean filter is the only barrier between your lungs and the microscopic allergens in your bedroom.

It's very important to keep CPAP machines and all of their supporting parts and equipment as clean as possible for the most effective CPAP therapy every night. Cleaning and maintaining your CPAP machine helps ensure healthy CPAP therapy and the long-term performance of your machine. Most cleaning and maintenance procedures are easy to follow and do not require special equipment or products to complete. Keep a routine schedule so your CPAP machine is always in top condition. Having proper sanitizing machines, such as the SoClean 2 or 3B Lumin can also be beneficial in keeping all your CPAP equipment clean.

Daily Cleaning of CPAP Equipment

Daily cleaning of your CPAP equipment should primarily focus on your CPAP mask. Get in a routine habit to always wipe down your CPAP mask after every use. Because your CPAP mask comes in direct contact with your face on a daily basis, it requires daily cleaning. Use warm water and a mild soap to wipe down your CPAP mask. This will help to eliminate and remove any oils or sweat that transferred for your face to your mask and could potentially weaken your mask's seal. Additionally, let the mask air-dry for several hours before putting it to use again.

It is also a good idea to wash your face before using your CPAP mask to prevent dead skin cells and oils from getting on the mask. Skin cells, sweat and oils from our skin may affect the mask seal, so daily face cleaning is also important for both hygiene and performance.

Weekly Cleaning of CPAP Equipment

A more thorough cleaning of your CPAP mask should be done weekly. Soak your mask in warm water and soap, rinse and let air dry. Weekly cleanings should also include your CPAP tubing. Bacteria and germs can grow in the tubing and weekly cleanings can help prevent these germs from infecting the air you breathe during CPAP therapy.  Much like the mask, soak the tubing in a soapy bath. Rinse and let air dry before putting the mask and tubing back together.

How To Clean the CPAP Mask Frame, Cushion and Headgear

The CPAP mask frame, cushions and headgear should also be cleaned weekly. Following a similar procedure with the CPAP mask and tubing, soak the parts in warm, soapy water. Rinse with clean water and allow to air dry before use. When soap and water are not available to you, having proper CPAP mask cleaning wipes are vital for a clean and sanitized CPAP therapy.

How To Clean the Air Tubing and Air Filter

When cleaning CPAP tubing, do not use any harsh chemicals as they can damage the tubing. Soap should be sufficient for disinfection. To clean reusable air filters, remove the filter and rinse under clean water. As you run it under the water, squeeze the filter to make sure there is no dust. Blot it dry with a  towel before reinstalling. Disposable filters should be replaced per the manufacturer’s instructions.

How To Clean the Humidifier Tube

If you use a humidifier with your CPAP machine, be sure to clean the tubing weekly with a warm, soapy water bath to prevent bacteria buildup from the moisture in the tube. Much like cleaning air tubing, avoid strong chemicals which can damage the tubing.

Recommendations For CPAP Replacement Supplies

Along with regular cleaning, replacing essential supplies is part of your CPAP machine maintenance.

  • Replace your CPAP mask every 6-12 months
  • Replace cushions every 3 months
  • Replace your headgear twice a year
  • Replace CPAP filters per the manufacturer’s instructions
  • Replace tubing every 90 days

Where Can I Buy a CPAP Cleaning and Sanitizing Machine?

You can also automate your cleaning process with a cleaning and sanitizing machine. You can find these sanitizing machines at The CPAP Shop. Our knowledgeable staff can help you choose a sanitizing machine that meets your needs. Give us a call at 866-414-9700.

It's very important to keep CPAP machines and all of their supporting parts and equipment as clean as possible for the most effective CPAP therapy every night. Cleaning and maintaining your CPAP machine helps ensure healthy CPAP therapy and the long-term performance of your machine. Most cleaning and maintenance procedures are easy to follow and do not require special equipment or products to complete. Keep a routine schedule so your CPAP machine is always in top condition. Proper sanitizing machines, such as the LiVilti PAPTIZER and React Health Lumin can also be beneficial in keeping all your CPAP equipment clean.

Daily Cleaning of CPAP Equipment

Daily cleaning of your CPAP equipment should primarily focus on your CPAP mask. Get in a routine habit to always wipe down your CPAP mask after every use. Because your CPAP mask comes in direct contact with your face on a daily basis, it requires daily cleaning. It only takes 30 seconds, and  it saves your skin and your mask seal.To do so:

  • Use warm water and a mild soap to wipe down your CPAP mask. This will help to eliminate and remove any oils or sweat that transferred from your face to your mask and could potentially weaken your mask's seal.
  • Let the mask air-dry for several hours before putting it to use again.

OR

  • Use a CPAP Mask Wipe to remove skin oils, sweat, and makeup. If oils sit on the silicone all day, they break down the material, leading to noisy leaks.

It is also a good idea to wash your face before using your CPAP mask to prevent dead skin cells and oils from getting on the mask. Skin cells, sweat, and oils from our skin may affect the mask seal, so daily face cleaning is also important for both hygiene and performance.

The water chamber can also be emptied everyday. Empty any remaining water. Rinse it and let it air dry upside down. Never leave standing water in your machine during the day, as it is a breeding ground for mold.

Weekly Cleaning of CPAP Equipment

A more thorough cleaning of your CPAP mask should be done weekly. Follow the following steps:

  • The Soak: Fill a sink with warm water and a mild, fragrance-free soap. Soak your mask (minus headgear), tubing, and water chamber for 30 minutes.

  • The Tube: Use a CPAP Tube Brush to scrub the interior of your hose. In 2026, specialized brushes are now available for "slim-line" and "heated" tubing to ensure you don't damage the internal copper wiring.

  • Rinse & Dry: Rinse thoroughly in cool water. Hang the tubing over a door or a dedicated CPAP Hose Hanger to ensure no water is trapped in the coils.

How to Clean the CPAP Mask Frame, Cushion, and Headgear

The CPAP mask frame, cushions, and headgear should also be cleaned weekly. Following a similar procedure with the CPAP mask and tubing, soak the parts in warm, soapy water. Rinse with clean water and allow to air dry before use. When soap and water are not available to you, having proper CPAP mask cleaning wipes is vital for a clean and sanitized CPAP therapy.

How to Clean the Air Tubing and Air Filter

When cleaning CPAP tubing, do not use any harsh chemicals as they can damage the tubing. Soap should be sufficient for disinfection. To clean reusable air filters, remove the filter and rinse under clean water. As you run it under the water, squeeze the filter to make sure there is no dust. Blot it dry with a towel before reinstalling. Disposable filters should be replaced per the manufacturer’s instructions.

How to Clean the Humidifier Tube

If you use a humidifier with your CPAP machine, be sure to clean the tubing weekly with a warm, soapy water bath to prevent bacteria buildup from the moisture in the tube. Much like cleaning air tubing, avoid strong chemicals that can damage the tubing.

Recommendations for CPAP Replacement Supplies

Along with regular cleaning, replacing essential supplies is part of your CPAP machine maintenance.

  • Replace your CPAP mask every 6-12 months
  • Replace cushions every 3 months
  • Replace your headgear twice a year
  • Replace CPAP filters per the manufacturer’s instructions
  • Replace tubing every 90 days

The 2026 "Cleaning Machine" Update: UV-C vs. Ozone

The landscape of CPAP cleaners has shifted significantly.

  • Avoid Ozone: Most major manufacturers (ResMed, Philips, Fisher & Paykel) now explicitly state that using Ozone/Activated Oxygen cleaners can void your warranty and damage internal components.

  • Choose UV-C LED: Devices like the Lumin or 3B Paptizer use high-intensity UV-C light to kill 99.9% of bacteria in just 5 minutes. These are "dry" cleaners—meaning no chemicals and no waiting for parts to dry. Note: UV-C kills germs but does not remove physical dust or oils, so you still need to wash your mask manually.

The Distilled Water Debate

In 2026, "Distilled remains King." While some machines claim to handle tap water, distilled water is the only way to prevent calcium and mineral scale from forming on your heater plate.

Pro-Tip: If you are traveling and can’t find distilled water, bottled "purified" water is a better temporary fix than tap water.

Where to Buy CPAP Cleaning and Sanitizing Machines

You can also automate your cleaning process with a cleaning and sanitizing machine. You can find these sanitizing machines at The CPAP Shop. Our knowledgeable staff can help you choose a sanitizing machine that meets your needs. Give us a call at 866-414-9700.

Watch This Video on Cleaning CPAP Equipment at Home!

Recent posts

Share this Post


Chris Vasta

Chris Vasta is the president of The CPAP Shop and an expert in sleep and respiratory therapy. He often provides insights on product design and functionality on various manufacturers’ prototypes and is frequently tapped to provide reviews on new releases.